Early Inhalation Therapy Medications
Medications delivered by inhalation in the first four decades of the profession (1940s-1989) are featured.
Penicillin G was the first agent administered as an inhaled dry powder. By the late 1940s, Abbott produced the Aerohaler which was designed to deliver penicillin G.
Vaponefrin (racemic epinephrine) was nebulized and commonly administered in the treatment of upper airway edema and post-extrubation stridor.
Isuprel was trademarked in 1947.
Tergemist was described as a mucolytic aerosol solution containing "a detergent, potassium iodide, and distilled water."
. A capsule containing a dry powder of the agent, was inserted into the delivery device called the Spinhaler. The capsule was pierced and the powder was released and delivered to the patient on inspiration.
Ventolin was approved by the FDA in 1987.